Description

3-Methoxy-5-[4-(Trifluoromethoxy)Phenyl]Pyridine is a high-value fluorinated pyridine derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its core value lies in the unique combination of the pyridine scaffold with methoxy and trifluoromethoxy substituents, offering versatile reactivity and desirable physicochemical properties for complex molecule construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is utilized in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and anti-inflammatory drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the stability imparted by the trifluoromethoxy group.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for OLEDs or charge-transport layers, due to its electron-deficient aromatic system.
• Chemical Biology Probe: Useful for designing molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	3-Methoxy-5-[4-(Trifluoromethoxy)Phenyl]Pyridine
CAS No.	1261853-71-7
Molecular Formula	C13H10F3NO2
Molecular Weight	269.22 g/mol
Synonyms	5-[4-(Trifluoromethoxy)phenyl]-3-methoxypyridine; 3-Methoxy-5-(4-trifluoromethoxyphenyl)pyridine; 3-Methoxy-5-(4-(trifluoromethoxy)phenyl)pyridine; Pyridine, 3-methoxy-5-[4-(trifluoromethoxy)phenyl]-; 1261853-71-7
EINECS	Contact for details

Quality Control

Our 3-Methoxy-5-[4-(Trifluoromethoxy)Phenyl]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects with material produced to meet cGMP and ISO standards as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.