Description

Methyl 2-Bromo-6-Iodobenzoate is a high-purity, multi-halogenated aromatic ester building block of significant interest in advanced organic synthesis. This compound matters for its role as a versatile intermediate in constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists working on cross-coupling reactions, such as Suzuki-Miyaura and Buchwald-Hartwig aminations, to introduce functionalized benzoate motifs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing complex, multi-substituted benzene cores.
• Agrochemical Synthesis: Used in research and development of novel herbicides, fungicides, and insecticides where the benzoate scaffold is a critical structural component.
• Material Science Research: Serves as a building block for creating specialized monomers, ligands for catalysis, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions (e.g., Suzuki, Stille, Sonogashira) due to the orthogonal reactivity of the bromo and iodo substituents, allowing for sequential functionalization.
• Chemical Biology & Proteomics: Can be utilized to synthesize molecular probes and affinity tags for studying biological systems.

Basic Information

Product Name	Methyl 2-Bromo-6-Iodobenzoate
CAS No.	1261840-81-6
Molecular Formula	C8H6BrIO2
Molecular Weight	340.94 g/mol
Synonyms	Methyl 2-bromo-6-iodobenzoate; Benzoic acid, 2-bromo-6-iodo-, methyl ester; 2-Bromo-6-iodobenzoic acid methyl ester; Methyl o-bromo-o-iodobenzoate; Methyl 2-bromo-6-iodobenzenecarboxylate; 1261840-81-6; Methyl 2-Br-6-I-Benzoate
EINECS	Contact for details

Quality Control

Our Methyl 2-Bromo-6-Iodobenzoate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemical production, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (HPLC Area %)	≥98.0%
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.