Description

Methyl 2-Bromo-6-Cyanobenzoate is a high-purity, multi-functional organic building block essential for advanced chemical synthesis. This compound is valued for its unique molecular architecture, which incorporates both bromo and cyano functional groups on an aromatic ester, enabling precise and diverse derivatization. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules, such as active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging its halogen and nitrile groups for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic semiconductors and liquid crystal materials due to its rigid, substituted benzoate core.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic and R&D Laboratories: Utilized in methodological research for new organic transformations, such as palladium-catalyzed cyanation or Suzuki-Miyaura couplings.

Basic Information

Product Name	Methyl 2-Bromo-6-Cyanobenzoate
CAS No.	1261840-54-3
Molecular Formula	C9H6BrNO2
Molecular Weight	240.06 g/mol
Synonyms	2-Bromo-6-cyanobenzoic acid methyl ester; Methyl 2-bromo-6-cyanobenzoate; Benzoic acid, 2-bromo-6-cyano-, methyl ester; 6-Cyano-2-bromobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of Methyl 2-Bromo-6-Cyanobenzoate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and stored in a dark place to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Purity (GC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.