Description

Ethyl 6-(2,3-Difluorophenyl)Pyridine-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its specific difluorophenyl and pyridine carboxylate structure. This compound is of significant value for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular architecture. It is primarily sought by research institutions and manufacturers in the global pharmaceutical and agrochemical industries for developing new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel small-molecule drugs, especially those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Serves as a key synthon for developing new-generation herbicides and pesticides with enhanced efficacy and selectivity.
• Material Science: Used in research for creating functionalized ligands and organic frameworks for catalytic and sensing applications.
• Academic & Contract Research: Employed in university and CRO laboratories for medicinal chemistry programs and structure-activity relationship (SAR) studies.
• Fine Chemical Synthesis: Acts as a versatile building block for constructing more complex heterocyclic compounds in custom synthesis projects.

Basic Information

Product Name	Ethyl 6-(2,3-Difluorophenyl)Pyridine-2-Carboxylate
CAS No.	1261831-63-3
Molecular Formula	C14H11F2NO2
Molecular Weight	263.24 g/mol
Synonyms	Ethyl 6-(2,3-difluorophenyl)picolinate; 2-Pyridinecarboxylic acid, 6-(2,3-difluorophenyl)-, ethyl ester; 6-(2,3-Difluorophenyl)-2-pyridinecarboxylic acid ethyl ester; Ethyl 6-(2,3-difluorophenyl)-2-pyridinecarboxylate; 1261831-63-3; Difluorophenyl picolinate derivative
EINECS	Contact for details

Quality Control

Our Ethyl 6-(2,3-Difluorophenyl)Pyridine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.