Description

Methyl 2,5-Difluoro-4-Methoxybenzoate is a high-purity fluorinated aromatic ester building block of significant interest in advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought by research chemists and process development scientists for constructing active pharmaceutical ingredients (APIs) and other fine chemicals where the difluoromethoxy aromatic motif is required.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and oncology therapeutics.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the production of fluorinated aromatic compounds for electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Advanced Polymer Chemistry: Employed as a monomer or modifier to introduce fluorine into polymer backbones, improving chemical resistance, thermal stability, and surface properties.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new fluorination methodologies and creating complex molecular architectures.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules at various scales.

Basic Information

Product Name	Methyl 2,5-Difluoro-4-Methoxybenzoate
CAS No.	1261830-21-0
Molecular Formula	C9H8F2O3
Molecular Weight	202.16 g/mol
Synonyms	2,5-Difluoro-4-methoxybenzoic acid methyl ester; Methyl 2,5-difluoro-4-methoxybenzoate; Benzoic acid, 2,5-difluoro-4-methoxy-, methyl ester; 4-Methoxy-2,5-difluorobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2,5-Difluoro-4-Methoxybenzoate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in cGMP (Current Good Manufacturing Practice) environments for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.