Description

5-(4-(Trifluoromethoxy)Phenyl)Pyridin-3-Amine is a high-purity, advanced pharmaceutical intermediate featuring a unique trifluoromethoxy-substituted biphenyl-pyridine scaffold. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel small-molecule therapeutics targeting a range of disease pathways. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to incorporate its distinct physicochemical properties into new active compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially for central nervous system (CNS) and inflammatory targets.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging the stability imparted by the trifluoromethoxy group.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands in catalysis and material science applications.
• Chemical Biology Probes: Employed in the design of molecular probes for studying enzyme function and biological pathways.
• Functional Material Development: A component in the research of organic electronic materials and liquid crystals.

Basic Information

Product Name	5-(4-(Trifluoromethoxy)Phenyl)Pyridin-3-Amine
CAS No.	1261780-90-8
Molecular Formula	C12H9F3N2O
Molecular Weight	254.21 g/mol
Synonyms	3-Amino-5-[4-(trifluoromethoxy)phenyl]pyridine; 5-[4-(Trifluoromethoxy)phenyl]pyridin-3-amine; 3-Pyridinamine, 5-[4-(trifluoromethoxy)phenyl]-; 1261780-90-8; 5-(4-Trifluoromethoxyphenyl)pyridin-3-ylamine
EINECS	Contact for details

Quality Control

Our 5-(4-(Trifluoromethoxy)Phenyl)Pyridin-3-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade starting materials and research standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.