Description

Ethyl 3-(4-Bromo-3-Fluorophenyl)Propanoate is a high-purity, synthetic organic compound belonging to the class of fluorinated aromatic esters. This specialty chemical serves as a critical building block (advanced intermediate) in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily required by R&D chemists and process development scientists for constructing active pharmaceutical ingredients (APIs) and other fine chemicals where precise bromo and fluoro substitution patterns are essential.

Application

This compound is a versatile intermediate designed for advanced synthetic chemistry. Its primary applications include:

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and other therapeutic small molecules.
• Agrochemical Synthesis: Used in the research and development of new generation pesticides, herbicides, and fungicides where the bromo-fluorophenyl moiety imparts specific biological activity.
• Material Science Research: Serves as a monomer or precursor in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: An essential reagent for method development, cross-coupling reactions (e.g., Suzuki, Heck), and exploring new synthetic pathways in academic and industrial laboratories.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules under cGMP or research-grade conditions.

Basic Information

Product Name	Ethyl 3-(4-Bromo-3-Fluorophenyl)Propanoate
CAS No.	1261778-92-0
Molecular Formula	C11H12BrFO2
Molecular Weight	275.12 g/mol
Synonyms	Ethyl 4-Bromo-3-fluorohydrocinnamate; 3-(4-Bromo-3-fluorophenyl)propanoic acid ethyl ester; Ethyl (4-Bromo-3-fluorophenyl)propionate; 4-Bromo-3-fluorobenzene propanoic acid ethyl ester; Ethyl 3-(4-Bromo-3-fluorophenyl)propionate; NSC 106021; AI3-63200
EINECS	Contact for details

Quality Control

Our Ethyl 3-(4-Bromo-3-Fluorophenyl)Propanoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can be aligned with cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.