Description

3-Iodo-2-Methoxy-6-Chloropyridine is a high-purity halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable scaffold for constructing complex molecules, particularly in pharmaceutical and agrochemical research. This compound is essential for medicinal chemists and R&D professionals developing new active ingredients, offering precise reactivity for cross-coupling and functional group transformations.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Building block for developing new generation herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Used in the creation of specialized ligands, organic semiconductors, and liquid crystal materials.
• Cross-Coupling Reactions: Serves as a versatile electrophile in Suzuki, Stille, and Negishi couplings to form biaryl and heterobiaryl structures.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological systems and mechanisms.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and development-scale batches.

Basic Information

Product Name	3-Iodo-2-Methoxy-6-Chloropyridine
CAS No.	1261769-34-9
Molecular Formula	C6H5ClINO
Molecular Weight	269.47 g/mol
Synonyms	6-Chloro-3-iodo-2-methoxypyridine; 2-Methoxy-6-chloro-3-iodopyridine; 3-Iodo-6-chloro-2-methoxypyridine; 2-Chloro-5-iodo-6-methoxypyridine; 6-Chloro-2-methoxy-3-iodopyridine; Pyridine, 6-chloro-3-iodo-2-methoxy-; (6-Chloro-2-methoxypyridin-3-yl)iodide
EINECS	Contact for details

Quality Control

Every batch of 3-Iodo-2-Methoxy-6-Chloropyridine is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and compliance with your project requirements. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by HPLC, GC, NMR, and mass spectrometry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.