Description

4-Bromo-2-Chloro-5-Nitropyridine is a high-purity halogenated nitropyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a versatile intermediate for constructing complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), crop protection agents, and functional materials, where precise chemical functionality is paramount.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its halogen and nitro groups for bioactivity.
• Material Science Research: Serves as a building block for creating functionalized pyridine-based ligands, polymers, and liquid crystals.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for biological target validation.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.
• Nucleophilic Aromatic Substitution: The chloro and bromo substituents provide distinct sites for selective displacement with various nucleophiles.

Basic Information

Product Name	4-Bromo-2-Chloro-5-Nitropyridine
CAS No.	1261767-18-3
Molecular Formula	C5H2BrClN2O2
Molecular Weight	237.44 g/mol
Synonyms	2-Chloro-4-bromo-5-nitropyridine; 5-Nitro-2-chloro-4-bromopyridine; 4-Bromo-2-chloro-5-nitro-pyridine; Pyridine, 4-bromo-2-chloro-5-nitro-; 1261767-18-3; 2-Chloro-4-bromo-5-nitro-pyridine
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Chloro-5-Nitropyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality assurance supports your R&D and production needs with reliable, high-purity material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; ensure containers are kept tightly sealed to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.