Description

3-(2-Fluoro-4-Hydroxy-Phenyl)-Propionic Acid Methyl Ester is a high-purity fluorinated aromatic ester building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals, where the fluorine atom and phenolic hydroxyl group offer critical sites for further functionalization. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to incorporate fluorinated aromatic motifs into novel molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel drug candidates, particularly in areas targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and pesticides with enhanced activity and selectivity.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for creating fluorinated aromatic components used in electronic display technologies.
• Polymer Modification: Incorporated as a monomer or modifier to impart specific properties like chemical resistance or altered polarity into specialty polymers.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development and exploring new fluorination chemistry pathways.
• Fine Chemical Production: Acts as a versatile synthon for manufacturing complex fluorinated aromatic compounds for various specialty applications.

Basic Information

Product Name	3-(2-Fluoro-4-Hydroxy-Phenyl)-Propionic Acid Methyl Ester
CAS No.	1261763-92-1
Molecular Formula	C10H11FO3
Molecular Weight	198.19 g/mol
Synonyms	Methyl 3-(2-fluoro-4-hydroxyphenyl)propanoate; 2-Fluoro-4-hydroxybenzenepropanoic acid methyl ester; Methyl 2-fluoro-4-hydroxyhydrocinnamate; 3-(2-Fluoro-4-hydroxyphenyl)propionic acid methyl ester; 1261763-92-1; Fluorinated hydrocinnamic acid methyl ester derivative; 4-Hydroxy-2-fluorophenylpropionic acid methyl ester
EINECS	Contact for details

Quality Control

Our 3-(2-Fluoro-4-Hydroxy-Phenyl)-Propionic Acid Methyl Ester is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance in cGMP and ISO 9001 environments where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.