Description

Ethyl 4-Chloro-5-Methylpicolinate is a high-purity, versatile picolinate ester derivative serving as a critical synthetic intermediate. Its value lies in providing a functionalized pyridine core essential for constructing complex molecules in advanced research and development. This compound is primarily needed by pharmaceutical, agrochemical, and specialty chemical manufacturers for applications in drug discovery, crop protection, and material science.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the pyridine moiety for bioactivity.
• Ligand and Catalyst Precursor: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials, such as electron-transport layers and light-emitting components.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A fundamental substrate for custom synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	Ethyl 4-Chloro-5-Methylpicolinate
CAS No.	1261739-13-2
Molecular Formula	C9H10ClNO2
Molecular Weight	199.63 g/mol
Synonyms	Ethyl 4-chloro-5-methylpyridine-2-carboxylate; 4-Chloro-5-methylpicolinic acid ethyl ester; 2-Pyridinecarboxylic acid, 4-chloro-5-methyl-, ethyl ester; 5-Methyl-4-chloropicolinic acid ethyl ester; Ethyl 4-chloro-5-methyl-2-pyridinecarboxylate; 1261739-13-2; 4-Chloro-5-methylpicolinate ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 4-Chloro-5-Methylpicolinate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.