Description

6-Chloro-5-Fluoropyridine-3-Sulfonyl Chloride is a high-value, multi-functional chemical building block essential for advanced organic synthesis. Its core value lies in its dual reactive sites—the sulfonyl chloride and halogenated pyridine ring—which enable efficient derivatization into complex target molecules. This compound is critically needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Used in the creation of functional polymers and advanced materials requiring sulfonamide or sulfonate linkages.
• Chemical Research: Versatile reagent for constructing complex heterocyclic compounds in academic and industrial R&D settings.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in catalytic systems.

Basic Information

Product Name	6-Chloro-5-Fluoropyridine-3-Sulfonyl Chloride
CAS No.	1261737-06-7
Molecular Formula	C5H2Cl2FNO2S
Molecular Weight	249.04 g/mol
Synonyms	3-Chlorosulfonyl-6-chloro-5-fluoropyridine; 5-Fluoro-6-chloropyridine-3-sulfonyl chloride; 6-Chloro-5-fluoro-3-pyridinesulfonyl chloride; 6-Chloro-5-fluoropyridine-3-sulfonylchloride; 3-Pyridinesulfonyl chloride, 6-chloro-5-fluoro-; 1261737-06-7; 6-Chloro-5-fluoropyridine-3-sulfonic acid chloride
EINECS	Contact for details

Quality Control

Our 6-Chloro-5-Fluoropyridine-3-Sulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.