Description

2-Chloro-5-Methylpyridine-4-Carbonitrile is a high-value pyridine derivative and versatile chemical building block. This compound is essential for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, due to its reactive nitrile and chloro substituents. It is primarily sought after by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), advanced crop protection agents, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the development of novel drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging its pyridine core for biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of functionalized heterocyclic compounds for electronic materials and organic semiconductors.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up production in fine chemical manufacturing.

Basic Information

Product Name	2-Chloro-5-Methylpyridine-4-Carbonitrile
CAS No.	1261685-10-2
Molecular Formula	C7H5ClN2
Molecular Weight	152.58 g/mol
Synonyms	4-Cyano-2-chloro-5-methylpyridine; 2-Chloro-5-picoline-4-carbonitrile; 5-Methyl-2-chloropyridine-4-carbonitrile; 2-Chloro-5-methyl-4-cyanopyridine; 4-Pyridinecarbonitrile, 2-chloro-5-methyl-; 2-Chloro-5-methylisonicotinonitrile
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Methylpyridine-4-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for each shipment, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.