Description

2-Fluoro-4-Methyl-5-(4-(Trifluoromethoxy)Phenyl)Pyridine is a high-value, multi-functional heterocyclic building block featuring a pyridine core substituted with fluorine, methyl, and a trifluoromethoxy phenyl group. This compound matters for its role as a critical intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its unique fluorine-containing structure imparts desirable properties like metabolic stability and enhanced lipophilicity. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological or physical characteristics.

Application

• Key intermediate in the research and development of novel pharmaceutical candidates, particularly in kinase inhibitor programs.
• Building block for the synthesis of advanced agrochemicals, such as herbicides and fungicides, leveraging the trifluoromethoxy group for improved activity.
• Precursor in material science for the development of organic electronic materials, including ligands for OLEDs or catalysts.
• Versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Used in the preparation of liquid crystal compounds for display technologies.
• Intermediate for the synthesis of specialized dyes and pigments.

Basic Information

Product Name	2-Fluoro-4-Methyl-5-(4-(Trifluoromethoxy)Phenyl)Pyridine
CAS No.	1261654-57-2
Molecular Formula	C14H9F4NO
Molecular Weight	283.22 g/mol
Synonyms	5-[4-(Trifluoromethoxy)phenyl]-2-fluoro-4-methylpyridine; 2-Fluoro-4-methyl-5-[4-(trifluoromethoxy)phenyl]pyridine; 2-Fluoro-4-methyl-5-(4-trifluoromethoxyphenyl)pyridine; 1261654-57-2; 5-(4-(Trifluoromethoxy)phenyl)-2-fluoro-4-picoline
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-Methyl-5-(4-(Trifluoromethoxy)Phenyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality parameters. Our commitment to quality supports applications in regulated environments, and we can work with clients to meet specific analytical requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.