Description

Methyl 2-Chloro-5-(Trifluoromethoxy)Benzoate is a high-purity organic building block characterized by its unique trifluoromethoxy and chloro substituents on the aromatic ring. This compound is of significant commercial importance as a key synthetic intermediate in the development of advanced agrochemicals and pharmaceuticals. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and contract manufacturing sectors for constructing complex molecules with tailored biological activity.

Application

• Agrochemical Intermediate: A critical precursor in the synthesis of novel herbicides and insecticides, where the trifluoromethoxy group enhances lipophilicity and metabolic stability.
• Pharmaceutical Building Block: Used in medicinal chemistry for the construction of active pharmaceutical ingredients (APIs), particularly in scaffolds targeting central nervous system and inflammatory diseases.
• Liquid Crystal & OLED Material Synthesis: Serves as a starting material for creating specialized aromatic esters used in electronic display technologies.
• Custom Synthesis & Contract Manufacturing: Employed by CDMOs (Contract Development and Manufacturing Organizations) for pilot-scale and commercial-scale production of client-specific compounds.
• Research & Development: Utilized in academic and industrial labs for method development and exploring new chemical entities in material science.

Basic Information

Product Name	Methyl 2-Chloro-5-(Trifluoromethoxy)Benzoate
CAS No.	1261649-12-0
Molecular Formula	C9H6ClF3O3
Molecular Weight	254.59 g/mol
Synonyms	2-Chloro-5-(trifluoromethoxy)benzoic acid methyl ester; Methyl 2-chloro-α,α,α-trifluoro-p-anisate; Benzoic acid, 2-chloro-5-(trifluoromethoxy)-, methyl ester; Methyl O-trifluoromethyl salicylate derivative
EINECS	Contact for details

Quality Control

Our Methyl 2-Chloro-5-(Trifluoromethoxy)Benzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.