Description

3-Hydroxy-5-(2-Trifluoromethylphenyl)Pyridine is a specialized heterocyclic compound featuring a pyridine core substituted with a hydroxyl group and a trifluoromethylphenyl moiety, offering unique electronic and steric properties. This compound serves as a high-value intermediate in advanced organic synthesis, particularly valued for its role in constructing complex molecular architectures. It is primarily sought by pharmaceutical R&D and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides, leveraging the stability of the trifluoromethyl group.
• Ligand and Catalyst Development: Serves as a precursor for creating novel ligands in coordination chemistry and catalysis.
• Material Science Research: Investigated as a monomer or additive for specialty polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	3-Hydroxy-5-(2-Trifluoromethylphenyl)Pyridine
CAS No.	1261640-32-7
Molecular Formula	C₁₂H₈F₃NO
Molecular Weight	239.19 g/mol
Synonyms	5-(2-(Trifluoromethyl)phenyl)pyridin-3-ol; 3-Pyridinol, 5-[2-(trifluoromethyl)phenyl]-; 5-(α,α,α-Trifluoro-o-tolyl)-3-hydroxypyridine; 3-Hydroxy-5-(2-trifluoromethylphenyl)pyridine; 5-(2-Trifluoromethylphenyl)-3-hydroxypyridine
EINECS	Contact for details

Quality Control

Our production of 3-Hydroxy-5-(2-Trifluoromethylphenyl)Pyridine adheres to stringent internal quality protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy. Certificates of Analysis (COA) documenting all critical parameters are provided and available upon request to ensure full traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store under dry, inert conditions (e.g., nitrogen atmosphere) in a cool (15-25°C), dry place. Keep the container tightly sealed when not in use to prevent degradation from moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.