Description

Methyl6-Chloro-3-(4-(Trifluoromethyl)Phenyl)Picolinate is a high-purity, advanced pharmaceutical intermediate characterized by its specific halogenated and trifluoromethylated aromatic structure. This compound is of significant commercial value for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular modification. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new drug candidates and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially in oncology and central nervous system (CNS) therapeutic research.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, leveraging the biological activity of the picolinate and trifluoromethylphenyl motifs.
• Chemical Synthesis: Serves as a versatile precursor for creating complex molecules in medicinal and synthetic chemistry due to its reactive chloro and ester functional groups.
• Material Science: Potential application in the research and development of specialty polymers and advanced organic electronic materials.

Basic Information

Product Name	Methyl6-Chloro-3-(4-(Trifluoromethyl)Phenyl)Picolinate
CAS No.	1261598-96-2
Molecular Formula	C14H9ClF3NO2
Molecular Weight	315.67 g/mol
Synonyms	Methyl 6-Chloro-3-[4-(trifluoromethyl)phenyl]pyridine-2-carboxylate; 2-Pyridinecarboxylic acid, 6-chloro-3-[4-(trifluoromethyl)phenyl]-, methyl ester; 6-Chloro-3-(4-trifluoromethylphenyl)picolinic acid methyl ester; Methyl 6-chloro-3-(4-trifluoromethylphenyl)picolinate; Methyl 6-chloro-3-(α,α,α-trifluoro-p-tolyl)picolinate
EINECS	Contact for details

Quality Control

Our production of Methyl6-Chloro-3-(4-(Trifluoromethyl)Phenyl)Picolinate adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality system is designed to meet the rigorous standards required for pharmaceutical and advanced chemical synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.