Description

3-Methoxy-5-(Trifluoromethoxy)Benzoic Acid Methyl Ester is a high-purity, multi-functional aromatic ester building block designed for advanced chemical synthesis. This compound matters for its unique trifluoromethoxy and methoxy substituents, which are critical for modulating the lipophilicity, metabolic stability, and electronic properties of target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Serves as a versatile precursor for constructing novel herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Used in the synthesis of advanced organic electronic materials and liquid crystal compounds for displays and lighting applications.
• Polymer & Specialty Chemical Modifier: Incorporated into polymer backbones or as a side-chain modifier to impart specific chemical resistance, thermal stability, or surface properties.
• Chemical Research & Development: A valuable building block for academic and industrial research in organic synthesis, catalysis, and materials science.

Basic Information

Product Name	3-Methoxy-5-(Trifluoromethoxy)Benzoic Acid Methyl Ester
CAS No.	1261583-60-1
Molecular Formula	C10H9F3O4
Molecular Weight	250.17 g/mol
Synonyms	Methyl 3-Methoxy-5-(trifluoromethoxy)benzoate; Benzoic acid, 3-methoxy-5-(trifluoromethoxy)-, methyl ester; 3-Methoxy-5-trifluoromethoxy-benzoic acid methyl ester; Methyl 3-methoxy-5-[(trifluoromethyl)oxy]benzoate; 1261583-60-1; MFCD30566666
EINECS	Contact for details

Quality Control

Our 3-Methoxy-5-(Trifluoromethoxy)Benzoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0% (Area %)
Purity (GC)	≥97.0%
Water Content (KF)	≤0.5% w/w
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.