Description

Ethyl 3-Methoxy-4-(Trifluoromethoxy)Benzoate is a high-purity fluorinated aromatic ester building block of significant interest in advanced organic synthesis. Its core value lies in the unique trifluoromethoxy substituent, which imparts enhanced metabolic stability, lipophilicity, and electronic properties to target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Serves as a versatile precursor in the synthesis of novel herbicides, fungicides, and insecticides, where the trifluoromethoxy group can improve biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Used in the research and production of advanced electronic materials, where its aromatic and fluorinated structure contributes to desired dielectric and luminescent properties.
• Polymer Chemistry: Acts as a monomer or modifier in the synthesis of specialty polymers, coatings, and resins to enhance chemical resistance and thermal stability.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, esterifications, and functional group transformations to construct complex, fluorinated molecular architectures.

Basic Information

Product Name	Ethyl 3-Methoxy-4-(Trifluoromethoxy)Benzoate
CAS No.	1261582-69-7
Molecular Formula	C11H11F3O4
Molecular Weight	264.20 g/mol
Synonyms	Ethyl 3-Methoxy-4-(trifluoromethoxy)benzoate; Benzoic acid, 3-methoxy-4-(trifluoromethoxy)-, ethyl ester; 4-(Trifluoromethoxy)-3-methoxybenzoic acid ethyl ester; 3-Methoxy-4-trifluoromethoxybenzoic acid ethyl ester; Ethyl 3-methoxy-4-trifluoromethoxybenzoate; Ethyl 4-trifluoromethoxy-3-methoxybenzoate; CAS 1261582-69-7
EINECS	Contact for details

Quality Control

Our Ethyl 3-Methoxy-4-(Trifluoromethoxy)Benzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.