Description

Ethyl 3-Amino-4-Iodobenzoate is a high-purity, versatile iodinated benzoate ester derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of both an amino and an iodine functional group on the aromatic ring, enabling a wide range of coupling and derivatization reactions. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides, leveraging the iodine atom for further functionalization.
• Material Science Research: Acts as a monomer or functionalizing agent in the creation of specialty polymers and liquid crystals.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for imaging and diagnostic applications.
• Cross-Coupling Reactions: Serves as a reliable substrate in palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig aminations.
• Academic & R&D: A valuable reagent for methodological studies and exploring new synthetic pathways in university and corporate research laboratories.

Basic Information

Product Name	Ethyl 3-Amino-4-Iodobenzoate
CAS No.	1261569-51-0
Molecular Formula	C9H10INO2
Molecular Weight	291.09 g/mol
Synonyms	Ethyl 3-Amino-4-Iodobenzoate; 3-Amino-4-Iodobenzoic Acid Ethyl Ester; Benzoic acid, 3-amino-4-iodo-, ethyl ester; 4-Iodo-3-aminobenzoic acid ethyl ester; Ethyl 4-iodo-3-aminobenzoate; AI3-53197; ZINC000103014757; AKOS025310948; SCHEMBL21824027
EINECS	Contact for details

Quality Control

Every batch of Ethyl 3-Amino-4-Iodobenzoate is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.