Description

4-Chloro-3-Iodo-2-Methoxypyridine is a high-purity, multi-halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its unique halogen substitution pattern, which provides distinct reactivity for constructing complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used to construct active molecules for crop protection products, leveraging its halogen handles for further functionalization.
• Ligand and Catalyst Development: Serves as a scaffold for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the development of organic electronic materials and liquid crystals due to its electron-deficient pyridine core.
• Cross-Coupling Reactions: The iodine and chlorine substituents make it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Chemical Biology Probes: Used as a building block for synthesizing molecular probes and tags for studying biological systems.

Basic Information

Product Name	4-Chloro-3-Iodo-2-Methoxypyridine
CAS No.	1261562-56-4
Molecular Formula	C6H5ClINO
Molecular Weight	269.47 g/mol
Synonyms	2-Methoxy-4-chloro-3-iodopyridine; 3-Iodo-4-chloro-2-methoxypyridine; 4-Chloro-3-iodo-2-pyridinol methyl ether; 4-Chloro-3-iodo-2-methoxypyridine; 2-Methoxy-3-iodo-4-chloropyridine
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Iodo-2-Methoxypyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.