Description

Methyl 2-Chloro-3,4-Difluorobenzoate is a high-purity fluorinated aromatic ester building block of significant importance in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is primarily needed by R&D chemists and process development scientists working on active ingredients, specialty chemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), especially those containing difluorophenyl motifs.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and insecticides requiring specific halogenated aromatic structures.
• Liquid Crystal & OLED Materials: Used in the synthesis of fluorinated components for electronic display and lighting technologies.
• Polymer Chemistry: Monomer or modifier for introducing fluorine atoms into polymer backbones to alter thermal and chemical resistance.
• Cross-Coupling Reactions: Serves as a substrate in Suzuki, Stille, and other palladium-catalyzed coupling reactions to create biaryl systems.
• Organic Synthesis Research: A valuable reagent for academic and industrial research in exploring new fluorination methodologies and heterocycle formation.

Basic Information

Product Name	Methyl 2-Chloro-3,4-Difluorobenzoate
CAS No.	1261562-52-0
Molecular Formula	C8H5ClF2O2
Molecular Weight	206.57 g/mol
Synonyms	2-Chloro-3,4-difluorobenzoic acid methyl ester; Methyl 2-chloro-3,4-difluorobenzoate; Benzoic acid, 2-chloro-3,4-difluoro-, methyl ester; 3,4-Difluoro-2-chlorobenzoic acid methyl ester; Methyl 3,4-difluoro-2-chlorobenzoate; 2-Chloro-3,4-difluorobenzoic acid, methyl ester; Methyl ester of 2-chloro-3,4-difluorobenzoic acid
EINECS	Contact for details

Quality Control

Our Methyl 2-Chloro-3,4-Difluorobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee batch-to-batch consistency and traceability for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.