Description

3-(4-(Trifluoromethyl)Phenyl)Pyridin-4-Amine is a high-purity, advanced pharmaceutical intermediate featuring a pyridine core substituted with a trifluoromethylphenyl group. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring specific molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, especially those targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Research: Serves as a structural component in the development of new pesticides and herbicides, leveraging the biological activity of the pyridine and trifluoromethyl motifs.
• Material Science: Used in the research and development of organic electronic materials, such as ligands for organic light-emitting diodes (OLEDs) or charge-transport materials.
• Chemical Synthesis: Acts as a versatile amine-containing building block for coupling reactions (e.g., Buchwald-Hartwig amination) to create more complex chemical entities in medicinal chemistry.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and coordination chemistry due to its nitrogen donor atoms.

Basic Information

Product Name	3-(4-(Trifluoromethyl)Phenyl)Pyridin-4-Amine
CAS No.	1261494-14-7
Molecular Formula	C12H9F3N2
Molecular Weight	238.21 g/mol
Synonyms	4-Amino-3-[4-(trifluoromethyl)phenyl]pyridine; 3-(4-Trifluoromethylphenyl)-4-pyridinamine; 4-Pyridinamine, 3-[4-(trifluoromethyl)phenyl]-; 3-(p-Trifluoromethylphenyl)-4-aminopyridine; 4-Amino-3-(4-trifluoromethylphenyl)pyridine; 3-(4-(Trifluoromethyl)phenyl)pyridin-4-amine
EINECS	Contact for details

Quality Control

Our 3-(4-(Trifluoromethyl)Phenyl)Pyridin-4-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.