Description

1-Bromo-3-Isocyanato-2-Methyl-Benzene is a specialized aromatic isocyanate derivative, distinguished by the presence of both bromine and isocyanate functional groups on a methyl-substituted benzene ring. This unique bifunctional structure makes it a versatile and high-value building block for synthesizing complex organic molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and life sciences industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting specific receptors where the bromine atom allows for further functionalization via cross-coupling reactions.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, where the isocyanate group reacts with amines to form urea derivatives with specific biological activity.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the production of specialty polyurethanes and polyureas with tailored properties for high-performance coatings, adhesives, or elastomers.
• Chemical Research & Development: Employed as a critical reagent in medicinal chemistry and material science labs for structure-activity relationship (SAR) studies and library synthesis.
• Ligand and Catalyst Development: The reactive isocyanate and halogen sites make it useful for constructing sophisticated ligands for catalysis or molecular recognition applications.

Basic Information

Product Name	1-Bromo-3-Isocyanato-2-Methyl-Benzene
CAS No.	1261475-16-4
Molecular Formula	C8H6BrNO
Molecular Weight	212.05 g/mol
Synonyms	2-Methyl-3-bromophenyl isocyanate; 3-Bromo-2-methylphenyl isocyanate; 1-Bromo-3-isocyanato-2-methylbenzene; 2-Methyl-3-bromo-1-isocyanatobenzene; 3-Bromo-o-tolyl isocyanate; (3-Bromo-2-methylphenyl) isocyanate; Isocyanic acid, 3-bromo-2-methylphenyl ester
EINECS	Contact for details

Quality Control

Our production of 1-Bromo-3-Isocyanato-2-Methyl-Benzene adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for your synthetic processes. Every lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We are committed to supplying material that meets the exacting requirements of research and development, with specifications available to support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its moisture-sensitive (hygroscopic) nature, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation by atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.