Description

2-Methoxy-5-[4-(Trifluoromethyl)Phenyl]Pyridine is a high-value, multi-functional heterocyclic compound featuring a pyridine core substituted with methoxy and trifluoromethylphenyl groups. This structure is engineered to provide unique electronic and steric properties, making it a critical advanced intermediate for the synthesis of complex active molecules. It is primarily sought after by R&D and production teams in the pharmaceutical and agrochemical sectors for developing new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Serves as a core structural component in the research and production of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyridine and trifluoromethyl motifs.
• Material Science Research: Used in the development of organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs), due to its conjugated system.
• Chemical Research & Development: Employed as a versatile synthon in organic chemistry for constructing complex molecular architectures in academic and industrial R&D settings.
• Ligand and Catalyst Preparation: Acts as a precursor for creating specialized ligands used in catalytic systems for asymmetric synthesis and cross-coupling reactions.

Basic Information

Product Name	2-Methoxy-5-[4-(Trifluoromethyl)Phenyl]Pyridine
CAS No.	1261467-29-1
Molecular Formula	C14H12F3NO
Molecular Weight	267.25 g/mol
Synonyms	5-[4-(Trifluoromethyl)phenyl]-2-methoxypyridine; 2-Methoxy-5-(4-trifluoromethylphenyl)pyridine; 2-Methoxy-5-(α,α,α-trifluoro-p-tolyl)pyridine; 2-Methoxy-5-(4-(trifluoromethyl)phenyl)pyridine; 2-Methoxy-5-(p-trifluoromethylphenyl)pyridine; 5-(4-Trifluoromethylphenyl)-2-methoxypyridine; 2-Methoxy-5-(4-trifluoromethyl-phenyl)pyridine
EINECS	Contact for details

Quality Control

Our production of 2-Methoxy-5-[4-(Trifluoromethyl)Phenyl]Pyridine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to verify identity and purity. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.