Description

1H-Pyrrolo[3,2-B]Pyridine-5-Carboxylic Acid, Ethyl Ester is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its fused pyrrolopyridine scaffold, which serves as a privileged structure for designing novel bioactive molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors, receptor modulators, and other small-molecule therapeutics.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science Precursor: Serves as a building block for creating organic semiconductors, ligands for metal-organic frameworks (MOFs), and specialty polymers.
• Chemical Biology Probe: Utilized in medicinal chemistry to create tool compounds for target validation and pathway analysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects and library production.

Basic Information

Product Name	1H-Pyrrolo[3,2-B]Pyridine-5-Carboxylic Acid, Ethyl Ester
CAS No.	1261433-14-0
Molecular Formula	C10H10N2O2
Molecular Weight	190.20 g/mol
Synonyms	Ethyl 1H-pyrrolo[3,2-b]pyridine-5-carboxylate; Ethyl 7-azaindole-5-carboxylate; 5-(Ethoxycarbonyl)-1H-pyrrolo[3,2-b]pyridine; 1H-Pyrrolo[3,2-b]pyridine-5-carboxylic acid ethyl ester; 7-Azaindole-5-carboxylic acid, ethyl ester
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[3,2-B]Pyridine-5-Carboxylic Acid, Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.