Description

(E)-Methyl 3-(1,5-Naphthyridin-3-Yl)Acrylate CAS NO 1261399-16-9 is a high-value, heterocyclic acrylate derivative characterized by its conjugated naphthyridine-acrylate structure. This compound serves as a critical pharmaceutical intermediate and advanced building block in organic synthesis, enabling the construction of complex molecular architectures. It is essential for research and development teams in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used as a building block for developing new active ingredients with herbicidal or pesticidal properties.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Organic Synthesis: Employed in cross-coupling reactions, cycloadditions, and as a Michael acceptor due to its reactive acrylate moiety.
• Chemical Biology: Utilized in the design and synthesis of molecular probes and enzyme inhibitors for biochemical research.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new chemical spaces in medicinal chemistry.

Basic Information

Product Name	(E)-Methyl 3-(1,5-Naphthyridin-3-Yl)Acrylate
CAS No.	1261399-16-9
Molecular Formula	C₁₃H₁₀N₂O₂
Molecular Weight	226.23 g/mol
Synonyms	Methyl (2E)-3-(1,5-naphthyridin-3-yl)prop-2-enoate; (E)-Methyl 3-(1,5-naphthyridin-3-yl)acrylate; Methyl (E)-3-(1,5-naphthyridin-3-yl)acrylate; 3-(1,5-Naphthyridin-3-yl)acrylic acid methyl ester; 1,5-Naphthyridine-3-acrylic acid methyl ester; 1261399-16-9; Methyl 3-(1,5-naphthyridin-3-yl)acrylate (E)-
EINECS	Contact for details

Quality Control

Our (E)-Methyl 3-(1,5-Naphthyridin-3-Yl)Acrylate is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.