Description

tert-Butyl ((5-(Trifluoromethyl)-1H-Pyrrolo[2,3-B] Pyridin-4-Yl)Methyl)Carbamate is a high-purity, advanced pharmaceutical intermediate designed for precision synthesis. This compound is a critical building block in modern medicinal chemistry, valued for its role in constructing complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly in oncology and targeted therapy research.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel drug candidates, especially kinase inhibitors.
• Organic Synthesis Building Block: Used in complex multi-step syntheses to introduce the privileged 5-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine scaffold.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization programs in drug discovery.
• Bioconjugation & Probe Development: Serves as a starting material for creating labeled compounds or biochemical probes for diagnostic and research applications.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) for cGMP-scale production of clinical trial materials.

Basic Information

Product Name	tert-Butyl ((5-(Trifluoromethyl)-1H-Pyrrolo[2,3-B] Pyridin-4-Yl)Methyl)Carbamate
CAS No.	1261366-02-2
Molecular Formula	C14H16F3N3O2
Molecular Weight	315.29 g/mol
Synonyms	Boc-4-AMinoMethyl-5-trifluoroMethyl-7-azaindole; 4-(((tert-Butoxycarbonyl)aMino)Methyl)-5-(trifluoroMethyl)-1H-pyrrolo[2,3-b]pyridine; tert-Butyl N-[[5-(trifluoroMethyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]Methyl]carbaMate; 1H-Pyrrolo[2,3-b]pyridine, 4-(((1,1-diMethylethoxy)carbonyl)aMino)Methyl)-5-(trifluoroMethyl)-; 1261366-02-2; Boc-Aminomethyl-5-CF3-7-azaindole
EINECS	Contact for details

Quality Control

Our tert-Butyl ((5-(Trifluoromethyl)-1H-Pyrrolo[2,3-B] Pyridin-4-Yl)Methyl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.