Description

5-Chloro-4-(Dimethoxymethyl)-1H-Pyrrolo-[2,3-B]Pyridine CAS NO 1261365-92-7 is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyrrolopyridine core structure. This compound is of significant value for research and development in medicinal chemistry, serving as a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical companies, biotechnology firms, and contract research organizations (CROs) engaged in the development of targeted therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, particularly those targeting kinase inhibition.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a core scaffold for constructing final API molecules in oncology and antiviral research pipelines.
• Biochemical Tool Compound: Employed in biochemical assays and as a reference standard for analytical method development and validation.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	5-Chloro-4-(Dimethoxymethyl)-1H-Pyrrolo-[2,3-B]Pyridine
CAS No.	1261365-92-7
Molecular Formula	C11H11ClN2O2
Molecular Weight	238.67 g/mol
Synonyms	5-Chloro-4-(dimethoxymethyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 5-chloro-4-(dimethoxymethyl)-; 4-(Dimethoxymethyl)-5-chloro-1H-pyrrolo[2,3-b]pyridine; 5-Chloro-4-(dimethoxymethyl)-7-azaindole; Pyrrolo[2,3-b]pyridine, 5-chloro-4-(dimethoxymethyl)-; 1261365-92-7
EINECS	Contact for details

Quality Control

Our 5-Chloro-4-(Dimethoxymethyl)-1H-Pyrrolo-[2,3-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can be aligned with cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.