Description

2-(Dimethoxymethyl)-6-(Trifluoromethyl)-1,8-Naphthyridine is a high-value, multi-functional chemical intermediate characterized by its unique naphthyridine core and reactive dimethoxymethyl and trifluoromethyl substituents. This compound matters for its role as a critical building block in the synthesis of complex molecules, particularly in the development of advanced pharmaceuticals and agrochemicals. It is primarily needed by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate its specific structural motifs into novel active ingredients.

Application

• As a key synthetic intermediate in the research and development of novel pharmaceutical candidates, particularly in kinase inhibitor programs.
• Utilized in the construction of agrochemical active ingredients, where the trifluoromethyl group can enhance biological activity and metabolic stability.
• Serves as a versatile building block in organic synthesis for creating complex heterocyclic compounds and functionalized naphthyridines.
• Potential use in the development of advanced materials, such as organic semiconductors or ligands for catalytic systems.
• Employed in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.

Basic Information

Product Name	2-(Dimethoxymethyl)-6-(Trifluoromethyl)-1,8-Naphthyridine
CAS No.	1261365-78-9
Molecular Formula	C₁₂H₁₁F₃N₂O₂
Molecular Weight	272.22 g/mol
Synonyms	6-(Trifluoromethyl)-2-(dimethoxymethyl)-1,8-naphthyridine; 2-(Dimethoxymethyl)-6-(trifluoromethyl)-1,8-naphthyridine; 1,8-Naphthyridine, 2-(dimethoxymethyl)-6-(trifluoromethyl)-; 2-(Dimethoxymethyl)-6-trifluoromethyl-1,8-naphthyridine
EINECS	Contact for details

Quality Control

Our 2-(Dimethoxymethyl)-6-(Trifluoromethyl)-1,8-Naphthyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is sensitive to fluoride/strong alkali conditions and should be stored separately from such materials. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.