Description

Methyl 1,5-Naphthyridine-3-Carboxylate is a high-purity heterocyclic building block and pharmaceutical intermediate of significant commercial interest. This compound serves as a critical synthon in the development of novel active pharmaceutical ingredients (APIs) and advanced materials. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other biologically active molecules targeting various disease pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the naphthyridine core.
• Organic Synthesis Building Block: Employed in medicinal and combinatorial chemistry for constructing complex heterocyclic compounds due to its reactive ester and nitrogen-containing ring system.
• Material Science Research: Investigated as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic semiconductors.
• Chemical Reference Standard: Supplied to analytical laboratories for use as a high-purity standard in method development and quality control testing.

Basic Information

Product Name	Methyl 1,5-Naphthyridine-3-Carboxylate
CAS No.	1261365-76-7
Molecular Formula	C10H8N2O2
Molecular Weight	188.18 g/mol
Synonyms	1,5-Naphthyridine-3-carboxylic acid, methyl ester; Methyl 1,5-naphthyridine-3-carboxylate; 3-(Methoxycarbonyl)-1,5-naphthyridine; Methyl 1,5-naphthyridine-3-carboxylic acid ester; 1,5-Naphthyridine-3-carboxylic acid methyl ester; 3-Carbomethoxy-1,5-naphthyridine
EINECS	Contact for details

Quality Control

Our production of Methyl 1,5-Naphthyridine-3-Carboxylate adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with customer specifications and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.