Description

tert-Butyl (2,3-Dihydro-[1,4]Dioxino-[2,3-B]Pyridin-7-Yl)Carbamate is a high-purity, advanced pharmaceutical intermediate featuring a fused dioxino-pyridine heterocyclic structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) due to its role as a protected amine precursor. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules, particularly those targeting the central nervous system.
• API Development: Serves as a crucial precursor in research and development pipelines for new chemical entities (NCEs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized compounds.
• Chemical Biology Probes: Can be utilized in the development of molecular probes for biological target identification and validation.

Basic Information

Product Name	tert-Butyl (2,3-Dihydro-[1,4]Dioxino-[2,3-B]Pyridin-7-Yl)Carbamate
CAS No.	1261365-75-6
Molecular Formula	C12H16N2O4
Molecular Weight	252.27 g/mol
Synonyms	7-[(tert-Butoxycarbonyl)amino]-2,3-dihydro-1,4-dioxino[2,3-b]pyridine; tert-Butyl N-(2,3-dihydro-1,4-dioxino[2,3-b]pyridin-7-yl)carbamate; BOC-Dioxinopyridine Amine; 1,4-Dioxino[2,3-b]pyridin-7-amine, N-BOC-protected; 7-Boc-amino-2,3-dihydro-1,4-dioxino[2,3-b]pyridine; Carbamic acid, N-(2,3-dihydro-1,4-dioxino[2,3-b]pyridin-7-yl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl (2,3-Dihydro-[1,4]Dioxino-[2,3-B]Pyridin-7-Yl)Carbamate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.