Description

5-Bromo-2,3-Diiodopyridine is a highly functionalized pyridine derivative that serves as a critical multi-halogenated building block in advanced organic synthesis. Its unique halogen pattern offers distinct reactivity for selective cross-coupling and metal-halogen exchange reactions, enabling the precise construction of complex heterocyclic architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a scaffold for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers and light-emitting components.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Negishi couplings to introduce the pyridine core into larger molecular systems.

Basic Information

Product Name	5-Bromo-2,3-Diiodopyridine
CAS No.	1261365-44-9
Molecular Formula	C5H2BrI2N
Molecular Weight	449.79 g/mol
Synonyms	2,3-Diiodo-5-bromopyridine; 5-Bromo-2,3-diiodopyridine; Pyridine, 5-bromo-2,3-diiodo-; 5-Bromo-2,3-diiodo-pyridine; 1261365-44-9; 2,3-Diiodo-5-bromo-pyridine; SCHEMBL23806227; AKOS040759232
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-2,3-Diiodopyridine is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our products are supported by comprehensive Certificates of Analysis (COA) detailing specifications and results from advanced techniques including HPLC, GC, NMR, and mass spectrometry. We adhere to cGMP principles where applicable to support our customers in regulated development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to prevent moisture absorption and contamination. Handle and store in accordance with all applicable local and international regulations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥97.0% (Area %)
Purity (HPLC)	≥98.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	<20 ppm
Water Content (KF)	<0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.