Description

4-(Dimethoxymethyl)-5-(Trifluoromethyl)-1H-Pyrrolo[2,3-B]Pyridine is a high-value, advanced pharmaceutical intermediate characterized by its unique pyrrolopyridine core and trifluoromethyl functionality. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with enhanced metabolic stability and bioavailability. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drugs, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the biological activity of the pyrrolopyridine scaffold.
• Chemical Biology Probe: Serves as a core structure for creating molecular probes to study enzyme function and biological pathways.
• Material Science Research: Investigated as a potential monomer or functional additive for specialty polymers and electronic materials.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.

Basic Information

Product Name	4-(Dimethoxymethyl)-5-(Trifluoromethyl)-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	1261365-40-5
Molecular Formula	C12H11F3N2O2
Molecular Weight	272.23 g/mol
Synonyms	5-(Trifluoromethyl)-4-(dimethoxymethyl)-1H-pyrrolo[2,3-b]pyridine; 4-(Dimethoxymethyl)-5-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 4-(dimethoxymethyl)-5-(trifluoromethyl)-; CAS 1261365-40-5
EINECS	Contact for details

Quality Control

Our production of 4-(Dimethoxymethyl)-5-(Trifluoromethyl)-1H-Pyrrolo[2,3-B]Pyridine adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for research and development applications. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability, consistency, and reliability for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.