Description

2-Bromo-6-(Hydroxymethyl)-4-Iodopyridin-3-Ol is a high-value, multi-halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring bromine, iodine, and hydroxymethyl functional groups on the pyridine core, makes it an indispensable intermediate for constructing complex molecules. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used as a building block for developing new pesticides and herbicides, leveraging its halogenated structure for bioactivity.
• Ligand Synthesis: Serves as a starting material for the preparation of specialized ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the creation of molecular probes and tags for studying biological processes due to its reactive halogen sites.
• Functional Material Development: A valuable monomer or intermediate in the synthesis of advanced polymers and organic electronic materials.
• Cross-Coupling Reactions: The bromine and iodine substituents make it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.

Basic Information

Product Name	2-Bromo-6-(Hydroxymethyl)-4-Iodopyridin-3-Ol
CAS No.	1261365-32-5
Molecular Formula	C6H5BrINO2
Molecular Weight	329.92 g/mol
Synonyms	3-Hydroxy-2-bromo-6-(hydroxymethyl)-4-iodopyridine; 4-Iodo-2-bromo-6-(hydroxymethyl)pyridin-3-ol; 2-Bromo-4-iodo-6-(hydroxymethyl)-3-pyridinol; 1261365-32-5; 2-Bromo-6-(hydroxymethyl)-4-iodopyridin-3-ol; 3-Pyridinol, 2-bromo-6-(hydroxymethyl)-4-iodo-
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-6-(Hydroxymethyl)-4-Iodopyridin-3-Ol is manufactured and tested under strict quality management systems. We employ advanced analytical techniques including HPLC, GC-MS, and NMR to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing all critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be amber-colored or stored in a dark environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.