Description

2-(2-Fluoro-Benzyloxymethyl)-Piperidine Hydrochloride is a high-purity, fluorinated piperidine derivative supplied as a hydrochloride salt. This compound serves as a critical pharmaceutical intermediate and research chemical for the development of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams seeking to incorporate a fluorinated piperidine moiety into their target structures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to explore fluorination effects on potency and pharmacokinetics.
• Chemical Biology Probes: Serves as a precursor for developing labeled compounds or tool molecules for target identification and validation.
• Agrochemical Synthesis: Intermediate for creating novel crop protection agents and pesticides.
• Academic Research: Employed in university and institutional labs for methodological development in organic and heterocyclic chemistry.
• Custom Synthesis: Starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for clients.

Basic Information

Product Name	2-(2-Fluoro-Benzyloxymethyl)-Piperidine Hydrochloride
CAS No.	1261235-10-2
Molecular Formula	C14H19ClFNO
Molecular Weight	271.76 g/mol
Synonyms	2-[(2-Fluorobenzyl)oxymethyl]piperidine hydrochloride; 2-(2-Fluorobenzyloxymethyl)piperidine HCl; Piperidine, 2-[(2-fluorophenyl)methoxy]methyl]-, hydrochloride (1:1); 1261235-10-2; 2-(2-Fluoro-benzyloxymethyl)-piperidine HCl; 2-[(2-Fluorobenzyloxy)methyl]piperidine hydrochloride
EINECS	Contact for details

Quality Control

Our 2-(2-Fluoro-Benzyloxymethyl)-Piperidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting standards for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.