Description

2-(6-Bromo-Pyridin-2-Yloxymethyl)-Pyrrolidine-1-Carboxylic Acid tert-Butyl Ester CAS NO 1261231-92-8 is a high-purity, advanced pharmaceutical intermediate featuring a bromopyridine and a protected pyrrolidine moiety. This compound is critical for enabling complex molecular transformations in the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: A key building block in the research and development of new drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Ligand Synthesis: Used in the preparation of sophisticated ligands for catalysis and metal-organic frameworks (MOFs).
• Agrochemical Research: Serves as a precursor in the synthesis of novel pesticides and herbicides with specific biological activity.
• Chemical Biology Probes: Employed in the development of molecular probes for studying enzyme function and biological pathways.
• Peptidomimetic Chemistry: The pyrrolidine scaffold makes it valuable for creating peptidomimetics and conformationally restricted peptide analogs.
• Material Science: Potential use as a monomer or functional additive in the synthesis of specialized polymers.

Basic Information

Product Name	2-(6-Bromo-Pyridin-2-Yloxymethyl)-Pyrrolidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1261231-92-8
Molecular Formula	C16H23BrN2O3
Molecular Weight	371.27 g/mol
Synonyms	tert-Butyl 2-[[(6-bromo-2-pyridinyl)oxy]methyl]-1-pyrrolidinecarboxylate; 2-((6-Bromopyridin-2-yloxy)methyl)pyrrolidine-1-carboxylic acid tert-butyl ester; 1-Boc-2-((6-bromopyridin-2-yloxy)methyl)pyrrolidine; 2-[(6-Bromo-2-pyridyloxy)methyl]pyrrolidine-1-carboxylic acid tert-butyl ester; 2-(6-Bromopyridin-2-yloxymethyl)pyrrolidine-1-carboxylic acid tert-butyl ester; N-Boc-2-((6-bromopyridin-2-yloxy)methyl)pyrrolidine
EINECS	Contact for details

Quality Control

Our 2-(6-Bromo-Pyridin-2-Yloxymethyl)-Pyrrolidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP compliance for pharmaceutical development, and we can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.