Description

tert-Butyl 4-Acetylpyridin-3-Ylcarbamate is a high-purity, advanced pharmaceutical intermediate characterized by its pyridine and carbamate functional groups. This compound is a critical building block in modern organic synthesis, enabling the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for process development and scale-up.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting neurological and metabolic disorders.
• Agrochemical Research: Used in the development of new pesticides and herbicides due to its heterocyclic structure.
• Organic Synthesis Building Block: Serves as a versatile reagent for constructing more complex molecular architectures in academic and industrial R&D.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalytic systems and metal-organic frameworks (MOFs).
• Material Science Precursor: Potential use in the synthesis of functionalized polymers and advanced organic materials.

Basic Information

Product Name	tert-Butyl 4-Acetylpyridin-3-Ylcarbamate
CAS No.	1260892-75-8
Molecular Formula	C12H16N2O3
Molecular Weight	236.27 g/mol
Synonyms	tert-Butyl (4-acetylpyridin-3-yl)carbamate; 3-[[(1,1-Dimethylethoxy)carbonyl]amino]-4-acetylpyridine; 4-Acetyl-3-[(tert-butoxycarbonyl)amino]pyridine; BOC-4-Acetyl-3-aminopyridine; tert-Butyl N-(4-acetyl-3-pyridyl)carbamate; 1260892-75-8
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-Acetylpyridin-3-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply and traceability for critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.