Description

3-Chloro-5,6,7,8-Tetrahydro-1,6-Naphthyridine Hydrochloride is a high-purity, heterocyclic organic compound that serves as a critical building block in advanced chemical synthesis. Its value lies in its unique fused bicyclic structure, which is essential for constructing complex molecules with targeted biological activity. This intermediate is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing novel active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step synthesis of complex APIs where the naphthyridine core is a required pharmacophore.
• Agrochemical Research: Serves as a building block for developing new crop protection agents and herbicides due to its heterocyclic scaffold.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways.
• Material Science Research: Investigated as a precursor for creating novel organic ligands and functional materials.

Basic Information

Product Name	3-Chloro-5,6,7,8-Tetrahydro-1,6-Naphthyridine Hydrochloride
CAS No.	1260879-95-5
Molecular Formula	C8H10ClN2•HCl
Molecular Weight	207.09 g/mol (Free base: 169.63 g/mol)
Synonyms	3-Chloro-5,6,7,8-tetrahydro-1,6-naphthyridine HCl; 3-Chloro-5,6,7,8-tetrahydro-1,6-naphthyridine hydrochloride; 1,6-Naphthyridine, 3-chloro-5,6,7,8-tetrahydro-, hydrochloride; 3-Chloro-5,6,7,8-tetrahydro[1,6]naphthyridine hydrochloride; 1260879-95-5; AKOS026714023; ZINC000000001000; 3-Chloro-5,6,7,8-tetrahydro-1,6-naphthyridine monohydrochloride
EINECS	Contact for details

Quality Control

Our 3-Chloro-5,6,7,8-Tetrahydro-1,6-Naphthyridine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC for assay and impurity profiling, to meet the stringent requirements of pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and residual solvent content is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Single Maximum Impurity	≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.