Description

4-Bromo-2-(Piperidin-4-Yl)Pyridine is a high-value brominated heterocyclic building block that combines a pyridine core with a piperidine substituent. This molecular architecture makes it a critical intermediate for medicinal chemistry research and pharmaceutical development, particularly in the synthesis of novel bioactive compounds. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially kinase inhibitors and central nervous system (CNS) active compounds.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its versatile bromine handle for cross-coupling reactions.
• Agrochemical Synthesis: Intermediate in the development of new generation pesticides and herbicides.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic systems.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: A crucial starting material for custom synthesis projects requiring complex piperidine-pyridine scaffolds.

Basic Information

Product Name	4-Bromo-2-(Piperidin-4-Yl)Pyridine
CAS No.	1260848-37-0
Molecular Formula	C10H13BrN2
Molecular Weight	241.13 g/mol
Synonyms	4-Bromo-2-(4-piperidinyl)pyridine; 2-(Piperidin-4-yl)-4-bromopyridine; 4-Bromo-2-piperidin-4-ylpyridine; Pyridine, 4-bromo-2-(4-piperidinyl)-; 4-Bromo-2-(piperidin-4-yl)pyridine; 1260848-37-0; 4-Bromo-2-(4-piperidyl)pyridine
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-(Piperidin-4-Yl)Pyridine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and development. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.