Description

8-Fluoro-Imidazo[1,2-A]Pyridine-2-Carboxylic Acid Ethyl Ester is a high-value fluorinated heterocyclic building block essential for modern pharmaceutical and agrochemical research. This compound serves as a critical intermediate in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and metabolic disorders. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, especially in kinase inhibitor and GPCR modulator research.
• Agrochemical Research: Used in developing novel herbicides and fungicides, where the fluorine atom enhances bioavailability and metabolic stability.
• Chemical Biology Probes: Serves as a core scaffold for creating fluorescent tags or activity-based probes for target identification and validation.
• Material Science: Potential precursor for organic electronic materials and metal-organic frameworks (MOFs) due to its rigid, conjugated structure.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations for custom synthesis and library production for client projects.
• Academic Research: Utilized in university and institutional labs for methodological studies in fluorination and heterocyclic chemistry.

Basic Information

Product Name	8-Fluoro-Imidazo[1,2-A]Pyridine-2-Carboxylic Acid Ethyl Ester
CAS No.	1260843-88-6
Molecular Formula	C10H9FN2O2
Molecular Weight	208.19 g/mol
Synonyms	Ethyl 8-Fluoroimidazo[1,2-a]pyridine-2-carboxylate; 8-Fluoroimidazo[1,2-a]pyridine-2-carboxylic Acid Ethyl Ester; 1260843-88-6; Imidazo[1,2-a]pyridine-2-carboxylic acid, 8-fluoro-, ethyl ester; Ethyl 8-fluoroimidazo[1,2-a]pyridine-2-carboxylate
EINECS	Contact for details

Quality Control

Our 8-Fluoro-Imidazo[1,2-A]Pyridine-2-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to light and potential reactivity with strong bases, the container should be kept sealed and separated from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.