Description

Ethyl 3-(5-Aminopyridin-3-Yl)Propanoate is a high-purity organic building block featuring both an amino group and an ester functionality on a pyridine scaffold. This compound is a critical intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by research institutions and industrial manufacturers for developing active pharmaceutical ingredients (APIs) and advanced crop protection agents. The CAS number for this compound is 1260824-37-0.

Application

This versatile chemical intermediate enables the synthesis of a wide range of specialized compounds. Its primary applications include:

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its pyridine-based structure.
• Chemical Research & Development: Serves as a versatile precursor in organic synthesis for creating complex heterocyclic compounds in academic and industrial R&D labs.
• Material Science: Potential use as a monomer or functionalizing agent in the development of specialty polymers and advanced materials.

Basic Information

Item	Details
Product Name	Ethyl 3-(5-Aminopyridin-3-Yl)Propanoate
CAS No.	1260824-37-0
Molecular Formula	C10H14N2O2
Molecular Weight	194.23 g/mol
Synonyms	5-Amino-3-pyridinepropanoic acid ethyl ester; Ethyl 3-(5-amino-3-pyridinyl)propanoate; 3-(5-Aminopyridin-3-yl)propionic acid ethyl ester; 1260824-37-0; Ethyl 5-aminonicotinatepropanoate; 3-Pyridinepropanoic acid, 5-amino-, ethyl ester; Ethyl β-(5-amino-3-pyridyl)propionate
EINECS	Contact for details

Quality Control

Our Ethyl 3-(5-Aminopyridin-3-Yl)Propanoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We can support development and commercial projects requiring compliance with cGMP, ICH Q7, and other relevant regulatory guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.