Description

2,6-Dimethyl-3-(Piperidin-3-Yl)Pyridine Dihydrochloride is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. Pharmaceutical R&D teams and fine chemical manufacturers need this precise intermediate to develop next-generation therapeutic compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of novel drug candidates, especially for neurological and oncological targets.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core scaffold or fragment in the design and development of new APIs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes within drug discovery.
• Biochemical Research: Employed as a tool compound or ligand in biochemical assays and receptor binding studies.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the production of clinical trial materials and commercial APIs.
• Process Chemistry: Used in route scouting, scale-up, and process optimization for efficient and cost-effective API manufacturing.

Basic Information

Product Name	2,6-Dimethyl-3-(Piperidin-3-Yl)Pyridine Dihydrochloride
CAS No.	1260821-02-0
Molecular Formula	C13H20N2 · 2HCl
Molecular Weight	285.23 g/mol (free base: 212.31 g/mol)
Synonyms	3-(3-Piperidinyl)-2,6-dimethylpyridine dihydrochloride; 2,6-Lutidine, 3-(3-piperidinyl)-, dihydrochloride; 3-(2,6-Dimethyl-3-pyridinyl)piperidine dihydrochloride; 2,6-Dimethyl-3-(3-piperidyl)pyridine dihydrochloride; 3-(2,6-Dimethylpyridin-3-yl)piperidine dihydrochloride
EINECS	Contact for details

Quality Control

Our 2,6-Dimethyl-3-(Piperidin-3-Yl)Pyridine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical development. Certificates of Analysis (COA) with full traceability are provided for every shipment, supporting compliance with cGMP and ICH Q7 guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.