Description

tert-Butyl 3-Bromopicolinate is a high-purity, versatile chemical intermediate essential for advanced organic synthesis. This compound is valued for its reactive bromine atom and the tert-butyl ester protecting group, which facilitate precise molecular construction in complex chemical environments. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs), ligands, and novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those containing pyridine or picolinate cores.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its halogenated heterocyclic structure.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig).
• Material Science Research: Employed in the development of organic electronic materials and functional polymers.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific, high-value brominated intermediates.

Basic Information

Product Name	tert-Butyl 3-Bromopicolinate
CAS No.	1260807-49-5
Molecular Formula	C10H12BrNO2
Molecular Weight	258.11 g/mol
Synonyms	3-Bromopyridine-2-carboxylic acid tert-butyl ester; tert-Butyl 3-bromo-2-pyridinecarboxylate; 2-Pyridinecarboxylic acid, 3-bromo-, 1,1-dimethylethyl ester; 3-Bromo-picolinic acid tert-butyl ester; t-Butyl 3-bromopicolinate
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Bromopicolinate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled and stored away from direct light exposure to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.