Description

4-Amino-3-Trifluoromethyl-Piperidine-1-Carboxylic Acid Benzyl Ester is a high-value, multi-functional piperidine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both an amino group and a trifluoromethyl substituent on the piperidine ring, makes it indispensable for modulating the physicochemical and pharmacological properties of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in central nervous system (CNS) and metabolic disease research.
• Agrochemical Synthesis: Used in the design and synthesis of novel pesticides and herbicides, where the trifluoromethyl group enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics Research: The piperidine scaffold is incorporated into peptide analogs to improve metabolic stability and bioavailability.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying enzyme function and biological pathways.
• Material Science: Potential monomer or additive for specialty polymers requiring specific fluorine-containing functionalities.

Basic Information

Product Name	4-Amino-3-Trifluoromethyl-Piperidine-1-Carboxylic Acid Benzyl Ester
CAS No.	1260804-09-8
Molecular Formula	C14H17F3N2O2
Molecular Weight	302.29 g/mol
Synonyms	Benzyl 4-Amino-3-(trifluoromethyl)piperidine-1-carboxylate; 1-Carbobenzyloxy-4-amino-3-trifluoromethylpiperidine; 4-Amino-3-trifluoromethyl-1-piperidinecarboxylic acid phenylmethyl ester; 1-N-Cbz-4-Amino-3-trifluoromethylpiperidine; N-Cbz-4-Amino-3-trifluoromethylpiperidine; 4-Amino-3-(trifluoromethyl)piperidine-1-carboxylic acid benzyl ester
EINECS	Contact for details

Quality Control

Every batch of 4-Amino-3-Trifluoromethyl-Piperidine-1-Carboxylic Acid Benzyl Ester is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.