Description

Methyl 2-(Bromomethyl)-5-(Trifluoromethyl)Nicotinate is a high-value, multi-functional chemical building block designed for advanced synthetic chemistry. This compound matters because it combines a reactive bromomethyl handle with a stable trifluoromethyl group and a methyl ester, enabling precise molecular construction in complex organic syntheses. It is primarily needed by pharmaceutical, agrochemical, and advanced materials research and development teams for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides and fungicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the creation of functionalized organic molecules for organic light-emitting diodes (OLEDs) and other electronic materials.
• Fluorine Chemistry Building Block: Essential for introducing the valuable trifluoromethyl moiety into target molecules to modulate their physicochemical properties.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	Methyl 2-(Bromomethyl)-5-(Trifluoromethyl)Nicotinate
CAS No.	1260672-86-3
Molecular Formula	C9H7BrF3NO2
Molecular Weight	298.06 g/mol
Synonyms	Methyl 2-(bromomethyl)-5-(trifluoromethyl)pyridine-3-carboxylate; 3-Pyridinecarboxylic acid, 2-(bromomethyl)-5-(trifluoromethyl)-, methyl ester; 2-(Bromomethyl)-5-(trifluoromethyl)nicotinic acid methyl ester; Methyl 2-bromomethyl-5-trifluoromethylnicotinate; 1260672-86-3
EINECS	Contact for details

Quality Control

Our Methyl 2-(Bromomethyl)-5-(Trifluoromethyl)Nicotinate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and GC-MS for solvent residue analysis. Certificates of Analysis (COA) with full batch traceability are provided to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.