Description

Methyl 3-(Bromomethyl)-2-Fluoropyridine-4-Carboxylate is a high-value, multi-functional pyridine derivative that serves as a critical building block in advanced organic synthesis. This compound is engineered to introduce both bromomethyl and fluoropyridine motifs into target molecules, enabling precise structural modifications. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging the fluoropyridine moiety for enhanced biological activity and environmental profile.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for electronic materials and organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions due to its reactive bromomethyl group.

Basic Information

Product Name	Methyl 3-(Bromomethyl)-2-Fluoropyridine-4-Carboxylate
CAS No.	1260672-78-3
Molecular Formula	C8H7BrFNO2
Molecular Weight	248.05 g/mol
Synonyms	Methyl 2-fluoro-3-(bromomethyl)isonicotinate; 2-Fluoro-3-(bromomethyl)isonicotinic acid methyl ester; 3-(Bromomethyl)-2-fluoropyridine-4-carboxylic acid methyl ester; Methyl 3-(bromomethyl)-2-fluoro-4-pyridinecarboxylate; 4-Pyridinecarboxylic acid, 3-(bromomethyl)-2-fluoro-, methyl ester; 1260672-78-3; 2-Fluoro-3-bromomethyl-isonicotinic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of Methyl 3-(Bromomethyl)-2-Fluoropyridine-4-Carboxylate is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting research and development standards. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to guarantee traceability and consistency for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.