Description

4-Pyridinecarboxylic Acid, 5-(Bromomethyl)-2-Chloro-, Methyl Ester is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, which combines halogenated and ester functionalities on a pyridine core, enabling precise chemical modifications. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex active molecules and novel chemical libraries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging its halogenated pyridine structure.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the preparation of functionalized organic molecules for organic light-emitting diodes (OLEDs) and other electronic materials.
• Chemical Biology Probes: Utilized to build molecular probes for studying enzyme function and biological pathways due to its reactive bromomethyl group.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring complex, halogenated heterocycles.

Basic Information

Product Name	4-Pyridinecarboxylic Acid, 5-(Bromomethyl)-2-Chloro-, Methyl Ester
CAS No.	1260671-90-6
Molecular Formula	C9H9BrClNO2
Molecular Weight	278.53 g/mol
Synonyms	2-Chloro-5-(bromomethyl)isonicotinic acid methyl ester; Methyl 2-chloro-5-(bromomethyl)isonicotinate; 5-(Bromomethyl)-2-chloro-4-pyridinecarboxylic acid methyl ester; Methyl 5-(bromomethyl)-2-chloropyridine-4-carboxylate; 2-Chloro-5-(bromomethyl)pyridine-4-carboxylic acid methyl ester; Isonicotinic acid, 5-(bromomethyl)-2-chloro-, methyl ester
EINECS	Contact for details

Quality Control

Our 4-Pyridinecarboxylic Acid, 5-(Bromomethyl)-2-Chloro-, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP and ISO standards ensures reliable supply for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. Due to its light-sensitive nature, handling should be performed under subdued lighting or in amber glass containers when possible.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.