Description

Ethyl 6-Chloro-5-Nitropicolinate is a high-purity, advanced pharmaceutical intermediate characterized by its specific halogenated and nitrated pyridine structure. This compound matters as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), enabling the development of new therapeutic agents. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for process development and scale-up activities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides due to its reactive nitro and chloro functional groups.
• Chemical Research: Serves as a versatile scaffold for heterocyclic chemistry and the creation of new chemical libraries.
• API Manufacturing: Employed in the production scale-up of specific active pharmaceutical ingredients requiring a functionalized picolinate core.
• Ligand and Catalyst Development: Useful in the preparation of specialized ligands for metal catalysis in fine chemical synthesis.

Basic Information

Product Name	Ethyl 6-Chloro-5-Nitropicolinate
CAS No.	1260669-90-6
Molecular Formula	C8H7ClN2O4
Molecular Weight	230.60 g/mol
Synonyms	Ethyl 6-chloro-5-nitropyridine-2-carboxylate; 5-Nitro-6-chloropicolinic acid ethyl ester; 2-Pyridinecarboxylic acid, 6-chloro-5-nitro-, ethyl ester; 6-Chloro-5-nitropicolinic acid ethyl ester; Ethyl 6-chloro-5-nitro-2-pyridinecarboxylate; 1260669-90-6; 6-Chloro-5-nitro-2-pyridinecarboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 6-Chloro-5-Nitropicolinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.