Description

3-Amino-6-Trifluoromethyl-Pyridine-2-Carboxylic Acid is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique structure, featuring both an amino and a carboxylic acid group on a trifluoromethylated pyridine core, makes it a critical intermediate for creating novel compounds with tailored properties. This product is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents, where the trifluoromethyl group can enhance biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis and metal-complex catalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers, organic semiconductors, and other advanced materials requiring specific electronic properties.
• Chemical Biology Probes: Useful for synthesizing labeled compounds and molecular probes for biochemical and diagnostic research applications.

Basic Information

Product Name	3-Amino-6-Trifluoromethyl-Pyridine-2-Carboxylic Acid
CAS No.	1260666-45-2
Molecular Formula	C7H5F3N2O2
Molecular Weight	206.12 g/mol
Synonyms	2-Pyridinecarboxylic acid, 3-amino-6-(trifluoromethyl)-; 3-Amino-6-(trifluoromethyl)picolinic acid; 6-(Trifluoromethyl)-3-aminopicolinic acid; 3-Amino-6-trifluoromethyl-2-pyridinecarboxylic acid; 3-Amino-6-trifluoromethylpicolinic acid; 3-Amino-6-trifluoromethyl-pyridine-2-carboxylic acid; 3-Amino-6-(trifluoromethyl)-2-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Amino-6-Trifluoromethyl-Pyridine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.